The Promises and Challenges of Tumor Mutation Burden as an Immunotherapy Biomarker: A Perspective From the International Association for the Study of Lung Cancer Pathology Committee

Last Updated: Friday, July 17, 2026

This article reviews the current clinical evidence for tumor mutation burden (TMB) as a biomarker and addresses the technical sequencing considerations and ongoing challenges in the use of TMB in routine practice.

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Translational Lung Cancer Research

Neoadjuvant Treatment of Stage IIIA-N2 in EGFR-Mutant/ALK-Rearranged Non–Small Cell Lung Cancer

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Biomarker Testing in Non-Small Cell Lung Cancer in Routine Care: Analysis of the First 3,717 Patients in the German Prospective, Observational, Nation-Wide CRISP Registry (AIO-TRK-0315)

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