From the publishers of JADPRO

Bone Protection Resource Center

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Association of bone mineral density testing with risk of major osteoporotic fractures among older men receiving androgen deprivation therapy to treat localized or regional prostate cancer

Last Updated: Friday, July 17, 2026

In a cohort study of 54,953 older men with prostate cancer, only 7.9% received dual-energy x-ray absorptiometry (DXA) screening within 12 months before and 6 months after beginning  androgen-deprivation therapy. However, testing of bone mineral density with DXA was significantly associated with a decreased risk of developing major osteoporotic fractures (HR, 0.91; 95% CI, 0.83-1.00; P = .05) after adjusting for propensity score.

JAMA Open Network
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